Heparin in the Treatment of Thrombosis.

This monograph presents the results of a comprehensive study of the anticoagulants, emphasizing their development, chemistry and clinical uses. It is written by a member of the Swedish school who is particularly interested in and has done much to develop heparin as a clinical agent and is, to that extent, biased. The chemical researches which are necessarily included for the sake of completeness are perhaps too technical for the average physician but serve nicely to illustrate the methods of research necessary to isolate and define compounds of therapeutic value. This would seem to be timely in view of the increasing number and importance of specific chemical agents. The clinical efficacy of heparin has been thoroughly evaluated in a large series of cases. Results, which seem to be valid, are certainly exciting and warrant much more clinical trial. Several important points are brought out which have not been emphasized in our