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The object of this note is to call attention to a third route for administering chemicals of the new group for excretory urography. In America, apparently, no attempts have been made along these lines, though intravenous and oral administration are well recognized. In 1931 Butzengeiger1first attempted subcutaneous skiodan in adults, using a 4 per cent (isotonic) solution and injecting 500 cc. containing 20 Gm. into the axillae. In thirty cases he reported results almost as satisfactory as those obtained by intravenous injection. The maximum excretion appeared from thirty to fifty minutes after injection, and there were no local or general deleterious effects. In 1932 Hillebrand2used this method in a child of 14 months with a renal tumor in whom intravenous injection was not possible. He used 100 cc. of a 4 per cent skiodan solution and obtained good results. The child died after the nephrectomy and
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Edwin Beer (1934) studied this question.
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