Numerical deconvolution of gas chromatograph peaks using Jansson's method

Severely overlapped gas chromatographic peaks can be resolved using Jansson's method. Jansson's method is an iterative nonlinear deconvolution technique and consists of Van Cittert's algorithm with the relaxation factor a function of the kth estimate of the peak shape. The maximum peak amplitude of the instrument and peak non‐negativity serve as constraints to improve the peak estimate. Super‐resolution is achieved without significantly degrading the chromatogram signal‐to‐noise ratio. The method only requires a knowledge of the instrument impulse response function and maximum peak height.