An up to 99:1 stereochemical excess of 3 is reported for the cycloreduction of the title enynes 1 using a palladium-based catalyst and formic acid. The two-step process involves β-elimination of the coordinated enyne to form diene 2, followed by 2 recoordinating and the regio- and stereoselective reduction to produce the γ,δ-unsaturated carbonyl product 3. R=carbonyl group.
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Oh et al. (2000) studied this question.
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