Why the study?
The ReStOre trial showed improved cardiorespiratory fitness in esophagogastric cancer survivors, but the biological effect of the exercise intervention on serum mediators of angiogenesis, inflammation, and vascular injury remained to be determined.
Does a 12-week rehabilitation program (ReStOre) alter serum biomarkers in disease-free esophagogastric cancer survivors?
Does a 12-week rehabilitation program (ReStOre) alter serum biomarkers in disease-free esophagogastric cancer survivors?
A 12-week exercise rehabilitation program significantly alters serum biomarkers of inflammation and vascular injury in esophagogastric cancer survivors.
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Exercise-induced biomarker changes in survivors need validation before clinical use; leaves open mechanistic ties to fitness gains.
Kennedy et al. (2021) studied this question.
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