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The potential development of blastomeres isolated from 255 mouse embryos in the 2-cell stage, 283 embryos in the 4-cell stage and 184 embryos in the 8-cell stage was compared. Results indicated that 44.6, 34.9 and 14.0% of these blastomeres, respectively, were capable of forming blastocysts in vitro. Transfers of cloned embryos into synchronized females was unsuccessful.
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Fiser et al. (1976) studied this question.
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