Peptide Functions in the Central Nervous SystemBrain Peptides as Neuronal MarkersMost degenerative neurologic disorders are characterized by premature cell death in discrete neuronal populations. In some cases, the cellular components affected can be characterized partly by their functional roles in neuronal systems. Further delineation of the cellular basis of such neurologic disorders may contribute important new information about their pathogeneses. Immunocytochemical characterization of the cell types that are commonly affected in degenerative diseases, together with measurement of regional peptide concentrations, may provide clues to the neuronal specificity (or lack of it) involved in a given disorder. It is . . .
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Krieger et al. (1981) studied this question.
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