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November 22, 2012Angewandte ChemieOpen Access

Mild and General Conditions for Negishi Cross‐Coupling Enabled by the Use of Palladacycle Precatalysts

Yang Yang Nathan J. Oldenhuis Stephen L. Buchwald

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Abstract

Ein breites Spektrum von Biarylen ist durch palladiumkatalysierte Negishi-Kreuzkupplungen bei Raumtemperatur oder mit geringen Katalysatormengen zugänglich, wobei die katalytisch aktive XPhosPd0-Spezies aus einem Aminobiphenyl-Palladacyclus erzeugt wird. Knifflige heterocyclische und polyfluorierte aromatische Substrate ergeben die Produkte in ausgezeichneten Ausbeuten.

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Yang et al. (2012) studied this question.

synapsesocial.com/papers/6a909623ebb21526730d5078 https://doi.org/10.1002/ange.201207750

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