Studies on Antifungal Activities of Econazole

Econazole had a potent fungicidal as well as fungistatic activity against many yeasts, yeast-like fungi and dermatophytes. This action was affected by neither composition of culture media nor their pH values, and was slightly inhibited by elongation of incubation time and increase in inoculum size. However, the influence of the blood was never negligible; particularly the lipid component seems to be principally attributable to the antagonistic effect of the blood.