The inflammatory reaction in regional enteritis is characteristically transmural, with affected loops of intestine frequently becoming attached to adjacent structures. As a result, deep ulcerations and fissures commonly lead to fistula formation rather than to free perforation into the peritoneal cavity. Over the past three years, we have encountered five cases of regional enteritis with free perforation. These cases and a review of the literature are presented in an attempt to clarify the pertinent factors leading to this complication.
No takes yet. Share an insight, caveat, or question.
Nasr et al. (1969) studied this question.