Boron Neutron Capture Radiography—Perspectives in Melanoma Therapy

Over t h e past decades, much interest has been focused on t h e possibility to develop drugs with selective affinity for receptors or other comDonents of tumour cells as a basis for diagnosis and therapy of malignant neoplasms. By using such compounds as carriers of stable nuclides, e.g. l0B, t h a t can later b e activated by neutron capture, an improvement in therapeutic efficacy and reduction of side effects may be combined. A distinct advantage of this approach is t h a t metastases would be targeted automatically.