Reduction of glycidyl mesylate with dissolving metal produces allylic alcohol in fair to excellent yield. Combined with the highly stereoselective epoxidation of allylic alcohols with t-butyl hydroperoxide and oxobis(2,4-pentanedionato-O,O′)vanadium(IV) as a catalyst, the sequence provides a new and efficient means for 1,3-trans-position of allylic alcohols, by which geraniol is transformed into linalool, farnesol into nerolidol, and furthermore, (−)-cis-carveol into the (+) antipode and vice versa in a stereospecific way.
No takes yet. Share an insight, caveat, or question.
Yasuda et al. (1979) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: