Follicular Lymphoma Revisited

The last quarter century has seen significant advances in the management and understanding of many human malignancies. This is especially true for the malignant lymphomas. The invitation to reflect on a report from Stanford, published 25 years ago, and the changes that have occurred since then, is a rare opportunity to look at what we have learned about the follicular non-Hodgkin’s lymphomas, generally, and their histologic and clinical transformation, specifically. It is useful to divide the Editorial into three parts: diagnostic advances, management advances, and transformation, of both the follicular lymphomas, but, also of the physicians who care for them.