This review summarizes the pathophysiology, presentation, diagnosis, and treatment of amiodarone-induced pulmonary toxicity.
Maintain vigilance for amiodarone pulmonary toxicity given diagnostic challenges; review extends guidance but leaves prospective validation open.
Amiodarone is widely used to prevent ventricular and supraventricular dysrhythmias but has a number of toxicities. One of the most devastating adverse reactions to this drug is pulmonary toxicity, which can present in a myriad of different ways. Toxicity is difficult to diagnose because many of its features also are seen in nontoxic patients. This article reviews the pathophysiology, presentation, diagnosis, and treatment of amiodarone-induced pulmonary toxicity.
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Colby et al. (2017) studied this question.
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