Provides a refined method for simultaneous estimation of intracellular free Mg2+ and pH using 31P-NMR in smooth muscle.
Enables refined Mg2+/pH estimation in smooth muscle models; leaves open translation to human cardiovascular research.
In the present technical note for 31P-NMR, we used a new pH-dependent dissociation constant of MgATP, and re-estimated changes in the intracellular free Mg2+ concentration and pH from the chemical shifts of beta- and gamma-ATP during Na+-removal in smooth muscle. We confirmed the role of Na+ - Mg2+ exchange.
No takes yet. Share an insight, caveat, or question.
Nakayama et al. (2002) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: