The etiologic role of EB virus in the pathogenesis of infectious mononucleosis has been strengthened by two recent large-scale prospective studies, one in the United States and the other in England.1 , 2 The results fully confirm previous observations made in Yale University students.3 4 5 6 7 In one study, as yet published only in abstract form, 800 Cornell students were investigated by Hirshaut et al.1 over a two-year period; 15 cases of clinical infectious mononucleosis occurred in the 200 students lacking EBV antibody, and none in those already possessing EBV antibody. In the other study, 1457 entering freshmen from six English universities and colleges . . .
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Alfred S. Evans (1972) studied this question.