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Highlight Severe malaria definitions guide treatment and triage but may not reflect traveller risks in non-endemic settings. Two recent studies found isolated hyperparasitemia in travellers rarely predicts critical disease, questioning the widely recommended need for intravenous (IV) therapy in such cases. Revisiting severity criteria could improve overall management and triage of malaria in travellers.
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Barkati et al. (2025) studied this question.
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