Hypoplasia of the Mandible (Micrognathy)

Atelectasis, congenital heart disease, intracranial hemorrhage and several other diseases are now recognized as producing cyanotic attacks in newly born infants, but little attention has been given to hypoplasia of the mandible as an etiologic entity in producing such attacks. During the past two years, four patients have been admitted to our wards on account of this condition. REPORT OF CASES Case1.—E. K., a white female infant, aged 6 weeks, was admitted to the hospital on account of failure to gain weight and frequent attacks of cyanosis. The family history was unimportant. The child was born at full term, with a normal delivery, weighing 8¼ pounds (3.7 Kg.). She was never breast fed but was given a formula on which she did not gain, though the formula was adequate. Soon after birth it was noticed that the infant had frequent and severe attacks of cyanosis, which could be relieved