Answers are grounded in this paper and cite their sources.
Immune doses of staphylococcal enterotoxin B to rabbits were studied by comparing the efficiency of various immunization schedules. It was experienced that even two subcutaneous injections each with such a small dose as 10 mug of enterotoxin B, the primary one with Freund's complete adjuvant and a booster one without adjuvant, could stimulate a rabbit to develop the antibody to a satisfactorily high titer determined by agar gel diffusion and passive hemagglutination.
No takes yet. Share an insight, caveat, or question.
Shinagawa et al. (1974) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: