A study of 34 patients was undertaken to determine the efficacy of a new antibiotic, cefoxitin sodium, in the treatment of abdominal sepsis. The most common infection was appendicitis associated with peritonitis. Thirty of the 34 patients were cured by cefoxitin therapy accompanied, when indicated, by surgical drainage. None of the patients developed adverse reactions to the antibiotic, but local pain related to i.v. injection was a common complaint.
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Geddes et al. (1978) studied this question.
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