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February 1, 1966Journal of Biological ChemistryOpen Access

Separation and Modification of the Phosphorolytic and Ribosyl Transfer Activities of the Purine Nucleoside Phosphorylase of Ehrlich Ascites Tumor Cells

Bernardo Bollen Pinto Oscar Touster

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Abstract

The separation of two types of catalytic activity exhibited by purine nucleoside phosphorylase purified from Ehrlich ascites tumor cells is described. Fractions catalyzing either phosphorolysis or ribosyl transfer were obtained by sucrose gradient centrifugation. Data regarding the conversion of phosphorolytic to transfer activity are presented, and observations relevant to the expression of the two catalytic activities are briefly discussed.

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Pinto et al. (1966) studied this question.

synapsesocial.com/papers/6a90e9de152a692a9d92d65c https://doi.org/10.1016/s0021-9258(18)96907-3

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