Why the study?
Does 2'-fluoro-2'-deoxycytidine (2'-FdC) inhibit Borna disease virus replication and spread without significant cytotoxicity?
Population
Borna disease virus (BDV) infection model
Design
Preclinical
Authors
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2'-FdC may support BDV antiviral development; leaves open clinical translation pending human studies.
Does 2'-fluoro-2'-deoxycytidine (2'-FdC) inhibit Borna disease virus replication and spread without significant cytotoxicity?
2'-FdC is a promising candidate for antiviral therapy against Borna disease virus due to its potent activity and negligible cytotoxicity.
Bajramović et al. (2004) studied this question.
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