Impact of Multidisciplinary Collaborative Intervention on Isolation Implementation in the Prevention and Control of Multidrug Resistance Infection—A Retrospective Study

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Background: Isolation is important in the prevention and control of infection with multidrug-resistant organisms(MDROs) but implementation is weak. We aim to analyze the impact of multidisciplinary collaborative intervention on isolation in multidrug-resistant organism(MDRO) infection and determine the factors affecting the implementation of isolation measures.Methods: A retrospective analysis of the issuance of isolation orders for 1338 patients with MDRO infection and colonization in 10 months before and after multidisciplinary collaborative interventions carried out on November 1, 2018 at a teaching tertiary hospital in central China. Univariate analysis and multivariate logistic regression analysis were used to analyze factors affecting isolation implementation. Results: The overall issuance rate of isolation orders was 66.12%, which increased from 33.12% before the intervention to 75.88% after the intervention (P <0.000). The multidisciplinary collaborative intervention (OR = 0.154) is a promoting factor for the issuance of isolation orders, in addition to Length of stay(LOS)> 15d (OR = 0.459) and department (P <0.05). Conclusions: Multidisciplinary collaborative interventions related to isolation can promote doctors to issue isolation orders in accordance with regulations.