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Expert perspective highlights ongoing gaps in vaccine efficacy across vulnerable populations, indicating a persistent clinical requirement for targeted respiratory syncytial virus therapeutics.
Respiratory syncytial virus infections recur throughout life despite induction of immunity by the first natural infection. An effective vaccine has long been sought but no vaccine is currently licensed, although promising candidates are currently being developed based on greater knowledge of the virus properties. However, there are significant populations that may not be protected adequately by a vaccine or are unable to be vaccinated. Thus, there is a continued need for effective therapeutic agents to treat the infection, especially in higher-risk individuals, a perspective presented in this article.
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Norbert J. Roberts (2023) studied this question.
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