Synthesis, Structural, and Physicochemical Study of First- and Second-Generation Melamine-Based Dendrimers

First-tier (G1) 2,4,6-tridiethymalonate-triazine (2,4,6-TDEMTA) and second-tier (G2) 2,4,6-hexadiethylmalonate-triazine (2,4,6-HDEMTA) dendrimers were prepared with melamine (1,3,5-triazine) as core (G0) and sodium malonate ester for bifurcation of chains. The trichlorotriazine (TCT) and sodium diethyl malonate (SDEM) aqueous solutions were mixed, and a creamy white precipitate of G1 was obtained. The G1 was hydrolyzed in alkaline medium to prepare 2,4,6-tridisodiummalonate-triazine (2,4,6-TDSMTA) by replacing −C2H5 groups of COOC2H5 by Na, which was further neutralized by dilute HCl to obtain 2,4,6-trimalonicacid-triazine (2,4,6-TMATA). The TMATA was treated with PCl5(s) to form –COCl, which was treated with SDEM to form the G2.