This case report describes a rare instance of splenic and hepatic angiosarcoma in an infant, representing the fifth reported case of splenic angiosarcoma in the pediatric age group.
Underscores lethality of infantile splenic angiosarcoma; extends sparse pediatric data but remains hypothesis-generating.
A 14-month-old white male was diagnosed as having angiosarcoma of both the liver and spleen. At 17 months he developed pulmonary metastases and died. There was no apparent environmental or hormonal exposure either prenatally or during infancy. The malignant tumor probably arose from its benign counterpart (hemangioendothelioma), which was found in the spleen. This is the fifth case reported of splenic angiosarcoma in the pediatric age group (18 years or younger).
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Alt et al. (1985) studied this question.
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