Why the study?
Does PCI within 12 hours of onset improve clinical outcomes compared to PCI at 12-24 hours in elderly high-risk patients with NSTEMI?
Does PCI within 12 hours of onset improve clinical outcomes compared to PCI at 12-24 hours in elderly high-risk patients with NSTEMI?
Very early PCI (within 12 hours) in elderly high-risk NSTEMI patients improves clinical outcomes compared to early PCI (12-24 hours) without increasing bleeding risk.
Answers are grounded in this paper and cite their sources.
Supports very early PCI in elderly high-risk NSTEMI; extends RCT timing evidence to this population.
Objective: To investigate the effect of treatment on prognosis of patients with different timing of early interventional treatment for non-ST segment elevation acute myocardial infarction (NSTEMI).Methods: Forty two cases above 75 years old, diagnosed with high-risk on NSTEMI, were selected in cardiology department of Xinxiang central hospital. They were randomly divided into two groups: 22 in group A and 20 in group B. Group A was performed PCI surgery within 12 hours after the onset while group B from 12 to 24 hour after the onset. Major adverse cardiovascular events (including death, heart failure readmission rates after ischemia, malignant arrhythmias, again target vessel revascularization) and bleeding data were recorded at the three terms of hospitalization, one month after the onset and six months after the onset.Results: Angina, malignant arrhythmia and heart failure during hospitalization can be reduced after interventional treatment carried out within 12 hours after the onset. Readmission rates after ischemia, heart failure and the incidence of death can be significantly reduced after interventional treatment carried out during 1-6 month after the onset with no significant increase in bleeding rate.Conclusion: In the treatment of elderly patients with NSTEMI, early interventional treatment is safe and effective.doi: http://dx.doi.org/-10.12669/pjms.315.7881How to cite this:Liu Z, Zhao L, Li Y, Wang Z, Liu L, Zhang F. Evaluation of early interventional treatment opportunity of the elderly & high-risk patients with non-ST segment elevation acute myocardial infarction. Pak J Med Sci 2015;31(5):1053-1056.
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Liu et al. (2015) studied this question.
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