May 1, 1987Muscle & Nerve

Contractile and EMG studies of murine myotonia (mto) and muscular dystrophy (dy/dy)

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Population

myotonic (mto) mouse and dystrophic mouse (dy/dy)

Design

Preclinical

Authors

RERichard K. EntrikinUniversity of California, Davis RARichard T. AbreschCarter Center RSRobert B. SharmanUniversity of California, Davis

Discussion

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Implication

These in vitro mto muscle defects extend model characterization; leaves open clinical translation to human myotonia.

Structured PICO

Population

myotonic (mto) mouse and dystrophic mouse (dy/dy)

Intervention

Tubocurarine (in vitro)

Outcome

Contractility (peak isometric tetanic tension, relaxation times) and electromyographic (EMG) dischargessurrogate

The mto mouse is a distinct myotonic mutant characterized by specific EMG discharges and contractile abnormalities that are partially responsive to tubocurarine in vitro.

Cite This Study

Entrikin et al. (1987) studied this question.

synapsesocial.com/papers/6a910cf6097347c7becae55f https://doi.org/10.1002/mus.880100403

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Contractile and EMG studies of murine myotonia (mto) and muscular dystrophy (dy/dy)

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Contractile and EMG studies of murine myotonia (mto) and muscular dystrophy (dy/dy)

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider