Why the study?
Despite many in vitro arterial simulator set-ups in the literature, organic research from a metrological and functional perspective is still lacking.
This review provides a metrological and functional classification of arterial simulators used for in vitro cardiovascular testing.
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Lack of metrological standards for arterial simulators warrants caution in in vitro cardiovascular testing; leaves open need for rigorous functional validation.
Arterial simulators are a useful tool to simulate the cardiovascular system in many different fields of application and to carry out in vitro tests that would constitute a danger when performed in in vivo conditions. In the literature, a thriving series of in vitro experimental set-up examples can be found. Nevertheless, in the current scientific panorama on this topic, it seems that organic research from a metrological and functional perspective is still lacking. In this regard, the present review study aims to make a contribution by analyzing and classifying the main concerns for the cardiovascular simulators proposed in the literature from a metrological and functional point of view, according to their field of application, as well as for the transducers in the arterial experimental set-ups, measuring the main hemodynamic quantities in order to study their trends in specific testing conditions and to estimate some parameters or indicators of interest for the scientific community.
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Fuiano et al. (2022) studied this question.
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