Population
27 patients with small cell osteosarcoma (SCO), median age 14 years (range 6 to 28), 12 male and 15 female.
Design
Case_series
Follow-up
up to 90 months
Authors
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Metastatic deaths predominate early in small cell osteosarcoma; leaves open whether novel systemic therapies can improve survival.
Small cell osteosarcoma is a high-grade variant with a prognosis similar to or slightly worse than conventional osteosarcoma, where distant metastases remain difficult to control.
Ayala et al. (1989) studied this question.
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