Answers are grounded in this paper and cite their sources.
Wnt growth factors function via Frizzled receptors to affect cellular proliferation, differentiation, apoptosis, and migration. Wnt/Frizzled signaling is now linked to human hereditary disorders with retinal vascular defects, implicating Wnts as angiogenic factors. Here, we discuss Wnts and a novel Frizzled ligand, Norrin, in physiological and pathological angiogenesis.
No takes yet. Share an insight, caveat, or question.
Masckauchán et al. (2006) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: