Resistance to clindamycin, erythromycin, and streptogramins in Clostridium difficile could be transferred to a susceptible strain by mixed culture at low frequencies (1 x 10(-8) to 4 - 10(-8) per donor cell). Transfer of tetracycline resistance occurred at frequencies of 3 x 10(-7) to 5 x 10(-7). No plasmid DNA involved in these transfers could be detected.
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Wüst et al. (1983) studied this question.