Anti-biofouling contact lenses bearing surface-immobilized layers of zwitterionic polymer by one-step modification

Poly(3-trimethoxysilyl-propyl-methacrylate) (PMPS) and poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) with various compositions was synthesized for the surface modification of currently commercially available lenses. The properties of these anti-biofouling contact lenses were investigated, which indicated that the modified contact lenses had significant surface-wettability improvement, superior antibacterial adhesion properties and resistance to protein adsorption. PMPS-b-PMPC can be immobilized on currently commercially available lenses by one-step modification while maintaining their excellent clinical performance and biocompatibility. The prepared anti-biofouling contact lenses may be realized in a more convenient and feasible way.