Nonspecific stimulation of the immune system of CBA mice carrying a functional BALB/c islet allograft failed to trigger graft rejection. Only three of six animals rejected their graft when injected intravenously with 10 5 , 10 6 , and 10 7 peritoneal cells of BALB/c origin over a 3-month period commencing 100 days after transplantation.
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Bowen et al. (1981) studied this question.
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