Observational study uncovers higher circulating IL-4R+SELL+ naïve B cells in chronic hepatitis B patients, indicating an immunological marker of functional cure.
Although hepatitis B surface antigen (HBsAg)-specific B cells have been partially characterized in chronic hepatitis B (CHB), the role of Naïve B cells and their potential relevance to functional cure remain insufficiently explored. Here, we aimed to characterize the naïve B-cell subsets between cured and uncured patients with CHB.
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Tang et al. (2026) studied this question.
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