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August 28, 2026BMC Cancer0 citationsOpen Access

Illness Perceptions and Associated Factors in Gastrointestinal Tract Cancer

‘How can I take things as they happen?’ unveiling illness perceptions among patients with gastrointestinal tract cancer: a mixed-methods study

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Authors

YCYongfeng ChenCCCarmen Wing Han ChanLZLiuxin Zhang

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Overview

Mixed-methods study reveals significant negative illness perceptions in gastrointestinal cancer patients, indicating that targeted education and psychosocial support can improve adaptive coping.

Key Points

  • Describe illness perceptions, identify associated clinical and demographic factors, and gain an in-depth understanding of disease representations among patients with gastrointestinal tract cancer.
  • Conducted a convergent mixed-methods study using the Brief Illness Perception Questionnaire (Brief-IPQ) across nine cognitive and emotional dimensions alongside semi-structured interviews.
  • Recruited 253 patients with gastrointestinal tract cancer from four tertiary hospitals in mainland China for quantitative evaluation, with 37 patients participating in qualitative content analysis.
  • Nearly one-third of patients exhibited moderate to high negative illness perceptions, with significantly worse scores associated with esophageal cancer, lower education, stage IV cancer, absence of surgery, and ECOG performance status ≥ 1.
  • Mixed-methods integration confirmed identity and cause dimensions while expanding understanding across consequences, timeline, personal control, treatment control, concern, emotional response, and comprehension.
  • Patients experienced elevated anxiety regarding prognosis and mortality, where insufficient management knowledge restricted personal control despite strong motivation to implement healthy lifestyle changes.

Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/6a91466cd15324a1df3a9fabhttps://doi.org/10.1186/s12885-026-16846-x
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