Population
Dogs (n=5)
Comparison
In vivo aging of biotinylated platelets vs Nonbiotinylated platelets (total population)
Design
Preclinical
Follow-up
5 days
Authors
Loading...
Aged platelets show reduced thrombin reactivity in mice; leaves open translation to human hemostasis or transfusion practice.
Increasing age of platelets in vivo impairs their reactivity to thrombin as measured by P-selectin expression.
Peng et al. (1994) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: