Why the study?
Does global longitudinal strain analysis detect myocardial abnormalities in children with latent rheumatic heart disease compared to healthy controls?
Population
139 Ugandan children, including 14 with definite rheumatic heart disease, 13 with borderline rheumatic heart…
Comparison
Global longitudinal strain analysis via standard… vs Healthy control subjects
Design
Case-control
Authors
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GLS may detect early myocardial involvement in latent RHD; hypothesis-generating and requires prospective validation before clinical use.
Does global longitudinal strain analysis detect myocardial abnormalities in children with latent rheumatic heart disease compared to healthy controls?
Global longitudinal strain is decreased in children with latent rheumatic heart disease despite normal systolic function, suggesting it may be a sensitive marker for early myocardial involvement.
Beaton et al. (2017) studied this question.
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