Squamous cell carcinoma is one of the most frequently recognized neoplastic diseases of the canine integument, although few risk factors influencing tumor development have been clearly defined. Three dogs with cutaneous squamous cell carcinomas are reported. Tumors developed in lightly-pigmented, glabrous following chronic sunlight exposure and long period of dermatosis. Microscopic examination of tissues from the three dogs showed progressive development of epithelial hyperplasia through stages of solar keratosis-like lesions to invasive and metastatic squamous cell carcinoma.
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Madewell et al. (1981) studied this question.
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