Facile one-pot synthesis of fluorescent hyperbranched polymers for optical detection of glucose

Fluorescent and glucose-sensitive hyperbranched poly(amidoamine)s (HPAMAMs-B) were synthesized via Michael addition of 1-(2-aminoethyl) piperazine, methyl acrylate, and 3-aminobenzeneboronic acid (APBA). These hyperbranched polymers emitted chartreuse photoluminescence and showed emission band at 378 nm under excitation wavelength. The intensity of emission band was enhanced with increasing the amount of APBA in HPAMAMs-B. The glucose sensitivity of HPAMAMs-B has been investigated at different glucose concentrations and pH conditions. These hyperbranched polymers showed potential for biomedical applications such as fluorescence imaging technology and glucose detecting sensors.