Candida Infections in Solid Organ Transplantation

Infections due to Candida spp are the most common invasive fungal infections (IFIs) among organ transplant recipients, accounting for over half of all IFIs in this population (1). In a large prospective study, invasive candidiasis had a 12-month cumulative incidence of 1.9%, the highest of all IFIs, and occurred more frequently in small bowel, pancreas, liver, kidney, heart and lung transplant recipients, in descending order (1). Invasive candidiasis occurs earlier than other invasive mycoses, generally within the first 3 months after transplantation, and is viewed as a classic nosocomial infection (2–6).