Why the study?
What are the epidemiological profile and prognostic factors for Ewing's sarcoma in a Brazilian pediatric population?
What are the epidemiological profile and prognostic factors for Ewing's sarcoma in a Brazilian pediatric population?
In a Brazilian cohort of patients with intraosseous Ewing's sarcoma, prognosis was primarily determined by the presence of metastases at diagnosis, corroborating established literature.
Metastases at diagnosis dictate prognosis in Brazilian pediatric Ewing sarcoma; confirms prior observations but leaves open need for prospective validation.
OBJECTIVE: To outline the epidemiological profile and prognosis for Ewing's sarcoma in the Brazilian population. MATERIAL AND METHODS: The medical records of 64 patients with intraosseous Ewing's sarcoma who were treated at the Pediatric Oncology Institute, IOP-GRAACC-Unifesp, between 1995 and 2010, were retrospectively evaluated. RESULTS: The statistical analysis on the data obtained did not correlate factors such as sex, trauma, pathological fracture and time taken for case diagnosis with the treatment outcome. Factors such as initial metastasis, lung metastasis, tumor site, age, recurrence and type of surgery showed results corroborating what has been established in the literature. CONCLUSION: The prognosis in cases of Ewing's sarcoma was mainly influenced by the presence of metastases at the time of diagnosis.
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Bellan et al. (2012) studied this question.
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