Answers are grounded in this paper and cite their sources.
Aldehydes accumulate in inflammation, during myocardial infarction and have been associated with pain symptoms. One pathway of aldehyde detoxification is the conjugation with carnosine. A 3-methylpyridinium carnosine adduct from the reaction of carnosine and acrolein was characterized using extensive spectroscopic measurements. The adduct with urinary concentrations of 1.82 ± 0.68 nmol/mg of creatinine is one of the most abundant acrolein metabolites in urine and opens promising therapeutic strategies for carnosine.
No takes yet. Share an insight, caveat, or question.
Bispo et al. (2016) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: