Hydrogel membranes consisting of copolymers from 2‐hydroxyethyl methacrylate (1a) and vinyl monomers (1b, 2b, 1c, 2c) containing nucleic acid bases such as adenine and uracil, were prepared by casting technique. The permeability measurement of these membranes for adenine and uracil revealed a selective transport which depends on the copolymer composition of the membranes and the permeation conditions. Transport of adenine based on the difference of proton concentration was also observed. The specific interaction between complementary nucleic acid bases seems to play an important role in the permeation behavior.
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Miyata et al. (1984) studied this question.
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