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Background: Calcium hydroxylapatite (CaHA) based soft-tissue filler (Radiesse® , Merz) is categorised as a biodegradable collagen-stimulating implant. It is comprised of a suspension of 25-45 micron diameter microspheres of CaHA(30%) in a carboxymethylcellulose (CMC) gel carrier (70%) and is one of the most well researched soft-tissue fillers. However, great discrepancies exist in the literature regarding the duration of clinical effect with the implant, ranging from only 6 to 24 months.
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Maria Angelo-Khattar (2021) studied this question.
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