Aim: To evaluate the Alere™ i Influenza A&B assay and the Xpert® Flu/RSV XC assay using nasopharyngeal aspirates and swabs not provided in the commercial kits. Methods: Specimens were tested with the Alere i Influenza A&B and the Xpert Flu/RSV XC assays and compared with reference methods. Results: Compared with the comparator methods and following discordant analysis, the sensitivity of the i Influenza A&B assay was 63.3% for influenza A and 83.3% for influenza B. For the Xpert Flu/RSV XC assay, sensitivity was 100% for influenza A and B and respiratory syncytial virus. The specificity for all test systems was 100%. Conclusion: The Xpert Flu/RSV XC assay out-performed the Alere i Influenza A&B assay in all diagnostic characteristics evaluated.
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Zelyas et al. (2017) studied this question.
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