Screening of fruits of seven plants indicated for medicinal use in Iraq

INTRODUCTION: Coumarins exert many biological effects in humans, animals, and plants, which make the evaluation of their biological activities and study of their role in ethnomedicine highly valued. OBJECTIVES: . MATERIALS AND METHODS: Seven plants were extracted by petroleum ether (PE) and ethanol (EtOH). Bergapten and methoxsalen were separated and purified by preparative thin-layer chromatography. Quantification of the furanocoumarins has been conducted by high-performance liquid chromatography, and all the plant extracts and pure compounds were checked for antibacterial activities utilizing alamar blue microplate assay. RESULTS: extract was least active, uncover the antibacterial role of bergapten and methoxsalen. CONCLUSION: family and quantify the two pharmacologically important furanocoumarins (bergapten and methoxsalen). SUMMARY: EtOH: Ethanol; MIC: Minimum inhibitory concentration; PE: Petroleum ether; Rf: Retardation factor; Rt: Retention time.