Key result
Radiofrequency catheter ablation in patients aged 75 years and older demonstrated similar primary efficacy (58.3% vs 63.0%, p=1.0) compared to younger patients.
Why the study?
Does radiofrequency catheter ablation provide similar efficacy and safety in elderly patients (≥75 years) compared to younger patients (<75 years) with drug-resistant atrial fibrillation?
Cohort (n=63)
No
Does radiofrequency catheter ablation provide similar efficacy and safety in elderly patients (≥75 years) compared to younger patients (<75 years) with drug-resistant atrial fibrillation?
Absolute Event Rate: 58.3% vs 63%
p-value: p=1.0
Radiofrequency catheter ablation for atrial fibrillation is as effective in patients aged 75 and older as in younger patients, though with a higher risk of manageable complications like hydrothorax.
May support ablation consideration in selected elderly AF patients; leaves open need for randomized safety confirmation.
Atrial fibrillation is one of the most frequent and significant rhythm disturbances. The effectiveness and expediency of using one of the most effective methods of treatment of this arrhythmia (radiofrequency ablation in elderly patients) remains a controversial and insufficiently studied issue. The article compares the results of the treatment of 63 patients of mature age (up to 75 years) and senile age (from 75 years). Patients underwent 78 operations of radiofrequency catheter ablation of atrial fibrillation and atypical atrial flutter, which was resistant to drug therapy. In the groups of patients of mature and senile age, there were no statistically significant differences in the effectiveness of treatment. In elderly people group, a higher incidence of complications was found mainly due to hydrothorax, but these complications did not increase the risk of death and were stopped during treatment. This allows to conclude that the senile age of patients should not be the reason for refusing to conduct radiofrequency catheter ablation.
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Fedorova et al. (2017) conducted a cohort in Atrial fibrillation and atypical atrial flutter (n=63). Age ≥75 years (senile age) vs. Age <75 years (mature age) was evaluated on Primary efficacy of radiofrequency catheter ablation (absence of arrhythmia recurrence after the first procedure) (p=1.0). Radiofrequency catheter ablation in patients aged 75 years and older demonstrated similar primary efficacy (58.3% vs 63.0%, p=1.0) compared to younger patients.
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