A follow-up examination of 152 patients with gastric ulcer treated with vagotomy, ulcerectomy and drainage showed that 4 of the patients manifested gastric cancer 5–7 years after the operation. A simultaneous follow-up of a parallel series of 269 patients with duodenal or pyloric ulcer treated with vagotomy and drainage in the same surgical unit did not reveal a single case of gastric cancer development. The observations seem to indicate that there is a greater risk of cancer development in the ulcerectomized and vagotomized stomach.
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Haukland et al. (2008) studied this question.