On the Persistence of R Factors in the Gram-Negative Aerobic Flora of the Human Intestine

Two groups of patients with predominant R+ enteric bacteria, one after treatment with antibiotics, and the other after infection or colonization with R+ pathogenic or non-pathogenic bacteria, were investigated half a year later. The influence of antibiotic therapy on the intestinal flora had almost disappeared at that time. In patients colonized with R+ bacteria from the environment or in which R+ strains had emerged during infection with R+ enteropathogenic bacteria the frequency of resistant bacteria including E. coli, and the incidence of R+ strains was significantly higher than in healthy subjects earlier studied.